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(1) Methodology for Estimating Demonstration Costs for FY 2024 Consistent with the general methodology from previous years, we are estimating the costs of the demonstration for the upcoming fiscal year, and proposing to incorporate this estimate into the budget neutrality offset amount to be applied to the national IPPS rates for the upcoming fiscal year, that is, FY 2024

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These research models allow investigators to examine peptide mediated signaling events, endocrine communication between tissues, and molecular mechanisms that influence energy metabolism and nutrient related signaling networks